货号: | T3066 |
CAS号: | 1160597-27-2 |
供应商: | 详询 |
数量: | 详询 |
英文名: | S-Ruxolitinib |
保质期: | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -3064℃ for several months. |
保存条件: | -20°C |
规格: | 2mg/5mg/10mg/25mg/50mg/1ml/10mM |
ID:T3066
PURITY:0.9975
Formula:C17H18N6
MolWt:360.36
Appearance:白色粉末
Solubility:G4DMSO 61 mg/mL;Water <1 mg/mL
Bioactivity:Ruxolitinib (INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3.
Status:FDA
Pathways:JAK/STAT Signaling
Target:JAK inhibitor
Receptor:JAK1, JAK2