货号: | T2620 |
CAS号: | 1457983-28-6 |
供应商: | 详询 |
数量: | 详询 |
英文名: | G-749 |
保质期: | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -2637℃ for several months. |
保存条件: | -20°C |
规格: | 1mg/5mg/10mg/25mg/50mg/1ml/10mM |
ID:T2620
PURITY:0.9924
Formula:C25H25BrN6O2
MolWt:521.41
Appearance:白色粉末
Solubility:G446 mM in DMSO
Bioactivity:G-749 is a novel and potent FLT3 inhibitor with IC50 of 0.4 nM, 0.6 nM and 1 nM for FLT3 (WT), FLT3 (D835Y), and Mer, respectively, showing lower potency against other tyrosine kinases.
Status:
Pathways:Angiogenesis
Target:FLT3 inhibitor
Receptor:FLT3;Mer;Aurora B;RET;VEGFR1/FLT1; Fms; Axl;Aurora C;FGFR1;FGFR3; VEGFR2/KDR; c-kit