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AHP1722T RABBIT ANTI HUMAN Bcl-xL
Jackson,JAC-211-492-171DyLight 649-
GUSB Antibody (OAAF03375)
[VIP第1年] 指数:1
通过认证 
caspase 3 （货号:664
HRP标记6*His标签抗体
双抗夹心法ELISA试剂
Zyxin Antibody| 货号： | 17952-1-AP |
| 克隆性： | 否 |
| 规格： | 50 ul/100 ul/150 ul |
Species specificity: human, mouse, rat
Positive WB detected in: mouse heart tissue, HepG2, HepG2 cells
Positive IP detected in: mouse heart tissue
Positive IHC detected in: mouse heart tissue, human heart tissue, human stomach cancer tissue, mouse heart tissue
Positive IF detected in: HEK-293 cells
PD-L1 (programmed cell death ligand 1, also known as CD274 or B7-H1) is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. PD-L1 is suggested a negative regulator of T and B cell, and play important role in mediating tolerance of lymphocytes to self-antigens. It also involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PD1-independent manner. PD-L1 is a 290 aa transmembrane protein with a calculated molecular weight of 33 kDa, the apparent molecular weight has been reported as 45-70 kDa, suggesting probable glycosylation (PMID: 18760278; 16493058).
温馨提示：不可用于临床治疗。
