货号: | OAAI00416 |
抗体英文名: | tsh Antibody (OAAI00416) |
靶点: | TSH |
应用范围: | ELISA, IHC, WB |
宿主: | Mouse |
适应物种: | Human |
克隆性: | 否 |
保存条件: | The antibodies are stable for 12 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C to 8C for three month without detectable loss of activity. Avoid repeated freezing thawing cycles. |
亚型: | Rabbit IgG |
免疫原: | A recombinant protein from the full length of Human TSH protein. |
规格: | 100 ug |
Swissprot Id: Q47692
The four Human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimmers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone, also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.
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Human anterior pituitary gl,
IHC: Human anterior pituitary gland tissue stained with Mouse anti TSH antibody, (Cat#OAAI00416) at 1:200 for 10 min @ RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
Human TSH protein
Western Blot: The full length of human TSH protein was immunoblotted by with Mouse anti TSH (Cat#OAAI00416) antibody at 1:500. An immunoreactive band is observed.