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GPX1 ELISA Kit (Bovine) (OKEH04607)

产品价格: ¥8832.00

最小起订量:暂无 可售数量:999盒

发货时限:
暂无
所在地区:
中国北京
有效期至:
长期有效
最后更新:
2021-05-20 01:30:01
浏览次数:
34

产品详情

品牌名称:
Aviva Systems Biology
货号: OKEH04607
适应物种: Bovine
规格: 96 Wells
NCBI Gene Id: 281209
Swissprot Id: P00435
The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance; therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. There is a direct correlation between the concentration of selenium and the activity of this enzyme in lactating cows, with the highest levels observed during the early stage of lactation, suggesting that the generation of reactive oxygen species was higher during this period compared to the late stage. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OKEH04607

GPX1 ELISA Kit (Bovine) (OKEH04607) standard curve using ELISA

GPX1 Standard Curve

Bovine GPX1 ELISA Kit standard curve

温馨提示:不可用于临床治疗。

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