货号: | OAPB01753 |
抗体英文名: | ULK1 Antibody - N-terminal (OAPB01753) |
靶点: | ULK1 |
应用范围: | ELISA, WB, IHC-P, IF |
宿主: | Rabbit |
适应物种: | Human, Mouse, Rat |
克隆性: | 否 |
保存条件: | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
形态: | Liquid, 1 mg/mL provided in PBS containing 0.02% sodium azide. |
亚型: | IgG |
免疫原: | ULK1 antibody was raised against a 16 amino acid peptide near the center of human ULK1 . |
规格: | 100 ug |
Swissprot Id: O75385
ULK1 Antibody: ULK1, also known as ATG1, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK1 results in a severe defect in the autophagy pathway. ULK1 is highly conserved among eukaryotes, and are the Unc-51-like kinases, ULK1 and ULK2 in mammals. ULK1 is ubiquitously expressed and involved in autophagy in response to starvation. It is the target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13. ULK1 also plays a role early in neuronal differentiation. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAPB01753
Brain tissue lysate
Western blot analysis of ULK1 in rat brain tissue lysate with ULK1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.