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羊抗人铁蛋白抗体（FE| 货号： | PL0300117 |
| 抗体名： | 过敏毒素C3受体抗体（补体C3受体） |
| 抗体英文名： | C3a Receptor/C3aR Antibody |
| 靶点： | C3a Receptor/C3aR |
| 浓度： | 1mg/ml |
| 应用范围： | WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500 |
| 宿主： | Rabbit |
| 适应物种： | Hu, Mo, Rat, Hor |
| 标记物： | 无标记（PLlabs可供应生物素、酶、荧光素标记的抗体） |
| 克隆性： | 否 |
| 保存条件： | 保存于-20℃ |
| 形态： | 液态 |
| 亚型： | Rabbit Polyclonal IgG |
| 免疫原： | Peptide derived from Hu C3a Receptor/C3aR. |
| 规格： | 0.1ml |
C3a Receptor/C3aR Antibody
Cat#：PL0300117
Isotype:Rabbit Polyclonal IgG
Immunogen：Peptide derived from Hu C3a Receptor/C3aR.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Complement C3 precursor contains complement C3 beta chain, complement C3 alpha chain, C3a anaphylatoxin, complement C3b alpha chain, complement C3c fragment, complement C3dg fragment, complement C3g fragment, complement C3d fragment and complement C3f fragment. C3a, C4a, and C5a are potent anaphylatoxins that are released during complement activation, a system of ligand-surface protein interactions specific to cells of hematopoietic lineage that aids in the elimination of pathogens. C3a and C5a secretion correlates with pathophysiological phenotypes such as asthma and bacterial meningitis. Binding of these proteins to their respective G protein-coupled receptors (C3aR, C5aR), which are present on the surface of myeloid leukocytes, induces proinflammatory events such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation and cellular chemotaxis. C3aR is expressed in brain and activated B-lymphocytes whereas C5aR is prevalent on the surface of hepatocyte, lung, smooth muscle, and endothelial cells. Upon activation, C3aR and C5aR are susceptible to rapid GRK-mediated phosphorylation and clathrin-coated vesicle targeting.
Alternate Names：
AZ 3B; AZ3B; C3a anaphylatoxin chemotactic receptor; C3A R; C3A R1; C3a-R; C3AR; C3AR_Hu; C3AR1; C3R1; Complement component 3 receptor 1; Complement component 3a receptor 1; HNFAG09.
Specificity Reaction：Hu, Mo, Rat, Hor
Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素（FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体，欢迎大家咨询订购。
温馨提示：不可用于临床治疗。
