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Annexin VIII Antibody (H-60)
Recombinant Human Interleukin 6, HE
兔抗小鼠IgG血清IgG
[VIP第1年] 指数:2
通过海淀分局认证 
| 货号： | IMS06-038-312 |
| 抗体英文名： | Fibrinogen, Biotin conjugated |
| 是否单克隆： | 否 |
| 抗原来源： | purified, full length native fibrinogen Q9UE34 |
| 宿主： | hen |
| 适应物种： | human |
| 数量： | 大量 |
| 规格： | 200 µl |
product information
background
Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N-terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases. The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel et al. 2000; Rapold et al. 1989).
immunogen
purified, full length native fibrinogen Q9UE34
antibody format
hen;
polyclonal;
affinity purified IgY at 1mg/ml in 0.15M sodium chloride, 0.02M sodium phosphate, 0.1 % sodium azide, pH 7.2;
liquid
quantity
200 µl
storage
store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
tested applications
Western blot (WB), immunodifusion (ID)
related products
IMS09-038-335 Fibrinogen | labelled with fluorescien
additional information
to be added when available
application information
recommended dilution
1: 5000 (WB)
expected | apparent MW
75 kDa
confirmed reactivity
human
predicted reactivity
bovine, mouse, porcine, rabbit, rat
not reactive in
no confirmed exceptions from predicted reactivity known in the moment
additional information
only one precipitation arc in immunodiffusion and immunoelectrophoresis against normal human plasma or human fibrinogen
selected references
to be added when available
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