货号: | YB-6655 |
生长状态: | 贴壁生长 |
年限: | 见说明书 |
运输方式: | 干冰运输or活细胞运输 |
器官来源: | 见说明书 |
是否是肿瘤细胞: | 见说明书 |
细胞形态: | 上皮样;多角形 |
免疫类型: | 请咨询销售人员 |
物种来源: | 人、大鼠、小鼠、、、、 |
组织来源: | 见说明书 |
ATCC Number: | 详见官方网站 |
细胞类型: | 复苏 |
供应商: | 钰博生物 |
数量: | 大量 |
Human Thrombin Introduction Thrombin enzyme (Activated Factor IIa) is an important clotting promoter that controls the transformation of soluble fibrinogen to insoluble active fibrin strands. Thrombin is a coagulation protein and a serine protease (EC 3.4.21.5) that catalyzes many coagulation-related reactions. Thrombin triggers factor-XI, factor-V, Factor-XIII and factor-VIII. Thrombin endorses platelet activation, using activation of protease-activated receptors on the platelet. As a result of its high proteolytic specificity, thrombin has become an important biochemical protein. The thrombin cleavage site (Leu-Val-Pro-Arg-Gly-Ser) is widely used in linker regions of recombinant fusion protein constructs. After the purification of the fusion protein, thrombin is used to cleave between the Arginine and Glycine residues of the cleavage site, efficiently removing the purification tag from the protein of interest with a high degree of specificity.
Human Thrombin Description Thrombin was purified from human plasma.
Source Human Plasma.
Physical Appearance Sterile filtered liquid formulation.
Human Thrombin Formulation The Factor-IIa contains 50mM sodium Citrate, 0.2M NaCl & 0.1% PEG-8000 pH 6.5.
Stability Human Thrombin although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Biological Activity The specific activity was found to be 3059 NIH Units/mg.
Human Thrombin Usage CHI's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.