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Recombinant Human IL-4

产品价格: ¥1310.00

最小起订量:暂无 可售数量:999盒

发货时限:
暂无
所在地区:
中国江西抚州市
有效期至:
长期有效
最后更新:
2021-05-08 01:30:02
浏览次数:
223

产品详情

品牌名称:
江蓝纯
货号: P00021
供应商: 江蓝纯
数量: 99
规格: 10ug/50ug /500ug/1mg
Known as Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor1; Pitrakinra; IL4
Derived from E.coli
Purity Measured by the dose-dependent stimulation of TF-1 cells.ED50 is less than 2 ng/ml. Specific Activity of 5.0 x 106 IU/mg.Greater than 95% as determined by reducing SDS-PAGE.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Shipping The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 5 months
Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in 3X PBS.Please aliquot the reconstituted solution to minimize freeze-t cycles.
Endotoxin Less than 0.1 ng/ug (1 IEU/ug).
Amino Acid Sequence MHKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAASKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRL DRNLWGLAGLNSCPVKEANQSTLENFLERLKTIMREKYSKCSS
Background Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.

Recombinant Human Interleukin-4 is produced by our E.coli expression system and the target gene encoding
His25-Ser153 is expressed.

温馨提示:不可用于临床治疗。

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