货号: | T1566 |
CAS号: | 129722-12-9 |
供应商: | 详询 |
数量: | 详询 |
英文名: | Aripiprazole |
保质期: | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -1605℃ for several months. |
保存条件: | -20°C |
规格: | 2mg/10mg/50mg/200mg/1ml/10mM |
ID:T1566
PURITY:0.99
Formula:C23H27Cl2N3O2
MolWt:448.39
Appearance:白色粉末
Solubility:G4DMSO > 10 mM
Bioactivity:Aripiprazole is an atypical antipsychotic medication used for the treatment of schizophrenia. It has also recently received FDA approval for the treatment of acute manic and mixed episodes associated with bipolar disorder. Aripiprazole appears to mediate its antipsychotic effects primarily by partial agonism at the D2 receptor. In addition to partial agonist activity at the D2 receptor, aripiprazole is also a partial agonist at the 5-HT1A receptor, and like the other atypical antipsychotics, aripiprazole displays an antagonist profile at the 5-HT2A receptor. Aripiprazole has moderate affinity for histamine and alpha adrenergic receptors, and no appreciable affinity for cholinergic muscarinic receptors.
Status:USAN, INN, BAN
Pathways:Neuroscience
Target:5-HT Receptor antagonist;AChR antagonist;Adrenergic Receptor antagonist ;Dopamine Receptor antagonist;Histamine antagonist
Receptor:5-HT receptor ;Muscarinic AChR;Adrenergic receptor;Dopamine receptor;Histamine H1 receptor