货号: | WL03028 |
抗体名: | DRP1 抗体 |
抗体英文名: | DRP1 antibody |
浓度: | >1mg/ml |
应用范围: | WB |
宿主: | 兔 |
适应物种: | H,M,R |
标记物: | 无 |
克隆性: | 否 |
保存条件: | -20℃ |
形态: | 液体 |
亚型: | IgG |
规格: | 50μl(>50μg) |
本公司所有一抗,50μl(>50μg)现价450元/支,全部现货,均提供20μl免费试用装,详情请点击免费试用
产品货号 | WL03028 | |||
产品名称 | DRP1 Antibody | |||
预测分子量 | 80 kDa | |||
别名 | DLP1; DNM1L; DVLP; EMPF; EMPF1; DYMPLE; HDYNIV; dynamin 1 like; Dynamin related protein 1 | |||
浓度 | >1 mg/ml | |||
免疫原 | 合成DRP1多肽 | |||
抗体来源 | 兔 | |||
特异性 | 抗人、小鼠、大鼠 | |||
克隆类型 | 多克隆抗体 | |||
产品应用 | WB | |||
成分 | 亲和纯化抗体,20 mM PBS,150 mM NaCl,100 μg/ml BSA,50%甘油,NaN3<0.02% | |||
保存条件 | -20℃保存 | |||
背景资料 | Drp1, which is a member of the dynamin superfamily of proteins, consists of a GTPase and GTPase effector domain that are separated from each other by a helical segment of amino acids. Drp1 is a fundamental component of mitochondrial fission. Indeed, Drp1 neurons have large, strongly interconnected mitochondria, due to dysfunctional fission machinery. ROS can be formed from incomplete transfer of electrons through the electron transport chain. Furthermore, fission influences calcium flux within the cell, linking Drp1 to apoptosis and cancer. In humans, loss of Drp1 function affects brain development and is also associated with early mortality. | |||
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