货号: | WL02477 |
抗体名: | mTOR 抗体 |
抗体英文名: | mTOR antibody |
浓度: | >1mg/ml |
应用范围: | WB,IHC |
宿主: | 兔 |
适应物种: | H,M,R |
标记物: | 无 |
克隆性: | 否 |
保存条件: | -20℃ |
形态: | 液体 |
亚型: | IgG |
规格: | 50μl(>50μg) |
产品货号 | WL02477 | |||
产品名称 | mTOR Antibody | |||
预测分子量 | predicted of mTOR: 289 kDa observed of mTOR: 211-245 kDa | |||
别名 | SKS; FRAP; FRAP1; FRAP2; RAFT1; RAPT1 | |||
浓度 | >1 mg/ml | |||
免疫原 | 合成mTOR多肽 | |||
抗体来源 | 兔 | |||
特异性 | 抗人、小鼠、大鼠 | |||
克隆类型 | 多克隆抗体 | |||
产品应用 | WB; IHC | |||
成分 | 亲和纯化抗体,20 mM PBS,150 mM NaCl,100 μg/ml BSA,50%甘油,NaN3<0.02% | |||
保存条件 | -20℃保存 | |||
背景资料 | The mammalian target of rapamycin (mTOR, FRAP, RAFT) is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to balance nutrient availability and cell growth. The phosphatidylinositol kinase (PIK) family members fall into two distinct subgroups. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. mTOR plays a key role in cell growth and homeostasis and may be abnormally regulated in tumors. For these reasons, mTOR is currently under investigation as a potential target for anti-cancer therapy. | |||
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