货号: | WL02967a |
抗体名: | SP1 抗体 |
抗体英文名: | SP1 antibody |
浓度: | >1mg/ml |
应用范围: | IHC |
宿主: | 兔 |
抗原来源: | 兔 |
适应物种: | H,M,R |
标记物: | 无 |
克隆性: | 否 |
保存条件: | -20℃ |
形态: | 液体 |
亚型: | IgG |
规格: | 50μl(>50μg) |
本公司所有一抗,50μl(>50μg)现价450元/支,全部现货,均提供20μl免费试用装,详情请点击免费试用
产品货号 | WL02967a | |||
产品名称 | SP1 Antibody | |||
别名 | Sp1 Transcription Factor; Sp1-1; SP1 | |||
浓度 | >1 mg/ml | |||
免疫原 | 合成SP1多肽 | |||
抗体来源 | 兔 | |||
特异性 | 抗人、小鼠、大鼠 | |||
克隆类型 | 多克隆抗体 | |||
产品应用 | IHC | |||
成分 | 亲和纯化抗体,20 mM PBS,150 mM NaCl,100 μg/ml BSA,50%甘油,NaN3<0.02% | |||
保存条件 | -20℃保存 | |||
背景资料 | Specificity protein 1 (SP1) is a ubiquitously expressed transcription factor belonging to the family of C2H2-type zinc finger containing DNA-binding proteins. SP1 binds GC-rich motifs with high affinity and regulates the expression of numerous mammalian genes. Although SP1 has been described as a transcriptional activator, it can also act as a repressor. SP1 has been implicated in the expression of numerous genes involved in many aspects of cellular life such as metabolism, cell growth, differentiation, angiogenesis and apoptosis regulation. Glycosylation of SP1 following insulin treatment leads to increased nuclear localization, while glucagon treatment increases cytoplasmic SP1 levels. | |||
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