货号: | PL0300854 |
抗体名: | WW结构域E3泛素连接酶1抗体 |
抗体英文名: | WWP1 Antibody |
靶点: | WWP1 |
浓度: | 1mg/ml |
应用范围: | WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500 |
宿主: | Rabbit |
适应物种: | Hu, Mo, Rat, Dog, Cow, Hor, Sheep, |
标记物: | 无标记(PLlabs可供应生物素、酶、荧光素标记的抗体) |
克隆性: | false |
保存条件: | 保存于-20℃ |
形态: | 液态 |
亚型: | Rabbit Polyclonal IgG |
免疫原: | Peptide derived from Hu WWP1. |
规格: | 0.1ml |
WWP1 Antibody
Cat#:PL0300854
Isotype:Rabbit Polyclonal IgG
Immunogen:Peptide derived from Hu WWP1.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
WWP1 is an E3 ubiquitin ligase and belongs to a family of NEDD4-like proteins. WWP1 contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. The HECT domain of WWP1 has been implicated in regulating the localization and stability of p53 鈥� inhibition of WWP1 results in a decrease in p53 expression, whilst WWP1 mediated stabilization of p53 appears to be associated with an accumulation of cytoplasmic p53.
Alternate Names:
AIP 5; AIP5; Atropin-1-interacting protein 5; hSDRP1; nedd4 like; NEDD4-like E3 ubiquitin-protein ligase WWP1; Tiul1; WW domain containing E3 ubiquitin protein ligase 1; WW domain-containing protein 1; WWP 1; WWP1_Hu.
Specificity Reaction:Hu, Mo, Rat, Dog, Cow, Hor, Sheep,
Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素(FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体,欢迎大家咨询订购。
温馨提示:不可用于临床治疗。