货号: | ABS 020-03 |
抗体名: | Anti-Peptide Histidine-Methionine (PHM) |
抗体英文名: | Anti-Peptide Histidine-Methionine (PHM) |
靶点: | 见说明书 |
浓度: | 见说明书 |
应用范围: | ELISA |
宿主: | Human |
供应商: | 上海信裕生物科技有限公司 |
数量: | 大量 |
级别: | 见说明书 |
目录编号: | ABS 020-03 |
抗原来源: | Human |
保质期: | 12个月 |
适应物种: | 见说明书 |
标记物: | 见说明书 |
克隆性: | 否 |
保存条件: | 4-8ºC without exposure to light. No precautions necessary during handling. |
形态: | 冻干粉/液体 |
亚型: | 见说明书 |
免疫原: | 见说明书 |
规格: | 200ug/1mg |
Anti-Peptide Histidine-Methionine (PHM)
- Cat. No.
- ABS 020-03
- Product name
- Anti-Peptide Histidine-Methionine (PHM)
- Description
- Mouse monoclonal antibody
- Specificity
- ABS 020-03 binds human PHM and cross-reacts with PACAP (approximately 12%; incomplete, non-parallel inhibition). ABS 020-03 does not cross-react with GLP-1, GLP-2, VIP or glucagon.
- Immunogen
- Synthetic human peptide histidine-methionine
- Application
- ELISA
- Species reactivity (positive)
- Human
- Species reactivity (negative)
- Not determined
- Subclass
- IgG2a/k
- Gene ID
- 7432
- Clone number
- 3
- Epitope
- Not determined
- Content
- Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
- Purification
- Protein-A purified
- Form
- Liquid
- Solvent
- 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
- Storage
- 4-8ºC without exposure to light. No precautions necessary during handling.
- Target
- Human peptide histidine-methionine (PHM) is a 27 amino acid peptide belonging to the glucagon-secretin family of peptide hormones. PHM is produced from the same prohormone as VIP, with which it shows considerable sequence homology. The VIP/PHM prohormone is produced by neurons in the central and peripheral nervous systems, often together with acetylcholine. In some situations the effect of the peptides is to reinforce and prolong the effects of neurotransmitter release. Like VIP, PHM is a vasodilator and stimulator of intestinal fluid secretion. High plasma levels of PHM are diagnostic of the corresponding peptide-producing tumor (VIPoma), associated with the watery diarrhea-hypokalemia-achlorhydria syndrome.