点击图片查看原图
MIR 3825 Label IT® DNP Nucleic Aci
DYKDDDDK-Tag(FLAG)，ARH4106【现货1-
HER2 Monoclonal Antibody
[VIP第1年] 指数:3
通过闵行区市场监督管理局认证 
IV型胶原蛋白/4型胶原
MicroVue CICP EIA*| 货号： | AK-520 |
| 抗体名： | Opioid Receptor Antibody Explorer Kit |
| 抗体英文名： | Opioid Receptor Antibody Explorer Kit |
| 靶点： | 见官方网站 |
| 浓度： | 见官方网站 |
| 应用范围： | 见官方网站 |
| 宿主： | 见说明书 |
| 供应商： | 上海信裕生物科技有限公司 |
| 数量： | 大量 |
| 级别： | 高 |
| 目录编号： | AK-520 |
| 抗原来源： | 见说明书 |
| 保质期： | 6个月 |
| 适应物种： | 见官方网站 |
| 标记物： | 见官方网站 |
| 克隆性： | 否 |
| 保存条件： | -20°C |
| 形态： | 液体或冻干粉 |
| 亚型： | 见官方网站 |
| 免疫原： | 见官方网站 |
| 规格： | 8 Vials |
Opioid Receptor Antibody Explorer Kit
A Screening Package of Opioid Receptor Antibodies Economically PricedCat #: AK-520
8 Vials
Alomone Labs is pleased to offer the Opioid Receptor Antibody Explorer Kit (#AK-520). The Explorer Kit contains opioid receptor antibodies, ideal for screening purposes.
- Compounds
- Scientific Background
Endogenous opiates such as endorphins, endomorphins, and enkephalins, as well as opiate drugs (including morphine) exert their effects by binding to opioid receptors. Three "classic" types of opioid receptors have been identified: mu (µ)-opioid (MOP) receptor, delta (δ)-opioid (DOP) receptor, and kappa (κ)-opioid (KOP) receptor.1 Recently, the nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor was also described. Despite its significant sequence homology, its pharmacological profile differs greatly from those of the classic µ, δ, and κ receptors.2
The opioid receptors belong to the G protein-coupled receptor (GPCR) superfamily whose members share a common structure of seven putative transmembrane domains, an extracellular amino terminus, a cytoplasmic carboxyl terminus, and a third intracellular loop important for binding G proteins.1
All three classic opioid receptors mediate opioid-induced analgesia. Supraspinal analgesia is mainly mediated by the µ-opioid receptor, whereas µ-, δ-, and κ-receptors participate in the control of pain at the spinal level.3 The opioid receptors also mediate the mood-altering properties of opioids.4 Cross-talk between µ- and δ- opioid receptors was demonstrated when subeffective doses of d-opioid receptors agonists modulated m-mediated analgesia.5
Opioid Receptor Antibody Explorer KitReferences
- Pan, L. et al. (2005) Neuroscience 133, 209.
- http://www.iuphar-db.org/DATABASE/FamilyIntroductionForward?familyId=50.
- Matthes, H.W. et al. (1998) J. Neurosci. 18, 7285.
- Di Chiara, G. and North, R.A. (1992) Trends Pharmacol. Sci. 13, 185.
- Vaught, J.L. et al. (1982) Life Sci. 30, 1443.
