货号: | bs-0330R-RBITC |
抗体名: | 罗丹明标记的兔抗小鼠k链 |
抗体英文名: | Rabbit anti-mouse Kappa light chain/RBITC |
靶点: | Rabbit anti-mouse Kappa light chain/RBITC |
浓度: | 2mg/1ml |
应用范围: | 详细信息请参考官网 |
宿主: | 兔 |
适应物种: | IgG |
标记物: | RBITC |
克隆性: | 否 |
保存条件: | Store at –20 C for one year. Avoid repeated freeze/thaw cycles. |
形态: | Lyophilized or Liquid |
亚型: | IgG |
免疫原: | KLH conjugated synthetic peptide derived from mouse Kappa li |
规格: | 0.1ml |
Immunoglobulins belong to a group of related glyco proteins which make up 20% of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit; while, IgM is a pen tamer. IgA may also form polymers. Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INV allotypic marker, Ala 45 and Leu 83.
温馨提示:不可用于临床治疗。
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