英文名称 | Rabbit PAK6 Polyclonal Antibody |
应用 | WB,IHC |
稀释比例 | WB1:500-1:2000 IHC1:50-1:200 |
交叉反应 | Human,Mouse,Rat |
蛋白分子量 | 75kDa |
Gene ID | 56924 |
保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | Recombinant protein of human PAK6 |
性状 | Lyophilized or Liquid |
Swiss Prot | Q9NQU5 |
克隆类型 | Polyclonal Antibody |
来源 | Rabbit |
背景资料 | This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. |