WNT Signaling Pathways: Canonical: APC, AXIN1, AXIN2, CSNK1A1, CTBP1, CTNNB1, CTNNBIP1 (ICAT), DKK1, DKK3, DVL1, DVL2, EP300, F1, FZD1, FZD2, FZD3, FZD4, FZD5, FZD6, FZD7, FZD8, FZD9, GSK3B, LEF1, LRP5, LRP6, NKD1, PORCN, RUVBL1, SFRP1, SFRP4, SKP2, SOX17, TCF7, TCF7L1, WIF1, WNT1, WNT10A, WNT2, WNT2B, WNT3, WNT3A, WNT4, WNT6, WNT7A, WNT7B, WNT8A.
Planar Cell Polarity (PCP): DAAM1, DVL1, DVL2, MAPK8 (JNK1), NKD1, PRICKLE1, RHOA, VANGL2, WNT9A.
WNT/Ca+2: FZD2, NFATC1, WNT1, WNT10A, WNT11, WNT2, WNT2B, WNT3, WNT3A, WNT4, WNT5A, WNT5B, WNT6, WNT7A, WNT7B, WNT8A, WNT9A.
WNT Signaling Negative Regulation: APC, AXIN1, AXIN2, BTRC (bTrCP), CCND1, CTBP1, CTNNBIP1 (ICAT), DKK1, DKK3, FBXW11, FRZB (FRP-3), KREMEN1, LRP6, NLK, NKD1, SFRP1, SFRP4, SOX17, WIF1.
WNT Signaling Target Genes: AXIN2, BTRC (bTrCP), CCND1, CCND2, DAB2, FOSL1 (FRA-1), JUN, MMP7, MYC, PITX2, PPARD, WISP1.
Developmental Processes: Cell Fate: CTNNB1,
DKK1, WNT1, WNT3, WNT3A.
Tissue Polarity: AXIN2, FZD2, FZD3, FZD5, FZD6, VANGL2.
Cell Growth & Prolifeion: APC, CCND1, CCND2, CTBP1, CTNNB1, CTNNBIP1 (ICAT), DAB2, EP300, FGF4, FOSL1, FZD3, JUN, LRP5, MMP7, MYC, PPARD, WISP1, WNT3A.
Cell Migion: APC, DKK1, LRP5, LRP6, RHOA, WNT1.
Cell Cycle: APC, BTRC (bTrCP), CCND1, CCND2, CTNNB1, EP300, FOSL1, JUN, MYC, RHOA, RUVBL1, TCF7L1.
Cellular Homeostasis: APC, FZD2, JUN, MYC.
Pathway Activity Signature Genes: BOD1, CALM1, CCND1, CCND2, CHSY1, CXADR, CYP4V2, HSPA12A, LEF1, MT1A, MTFP1, MTSS1, MYC, NAV2, PRMT6, SKP2.