货号: | AVARP09059_T100 |
抗体英文名: | CCR8 antibody - middle region (AVARP09059_T100) |
靶点: | CCR8 |
应用范围: | WB |
宿主: | Rabbit |
适应物种: | Cow, Human, Rabbit |
克隆性: | 否 |
保存条件: | Add 100 ul of distilled water. Final concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
形态: | Lyophilized |
免疫原: | The immunogen is a synthetic peptide directed towards the middle region of human CCR8 |
规格: | 100 ug |
Swissprot Id: P51685
CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. Its gene is located at the chemokine receptor gene cluster region. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet_lyophilized.php?sku=AVARP09059_T100
Human K562
WB Suggested Anti-CCR8 Antibody Titration: 2.5ug/ml
Positive Control: K562 cell lysate
CCR8 is supported by BioGPS gene expression data to be expressed in K562