货号: | ALP105 |
数量: | 5 |
Alport's Syndrome kit WIESLAB®
Patients with Alport syndrome have mutations in the gene for the alfa 5 chain of type IV collagen. This results in a lack of the alfa 5 (IV) chain from glomerular basement membrane (GBM) and the skin basement membrane as well as a lack of the alfa 3 (IV) chain from GBM. Analysis of kidney biopsies and skin biopsies for Alport syndrome can be tested for the presence or absence of the type IV collagen alpha-3, alpha-4 and alpha-5 chains (COL4A3, COL4A4, COL4A5).