货号: | CYT-270 |
规格: | 25mg |
Catalogue Number | CYT-270 | |||
Introduction | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | |||
Description | Insulin Human Recombinant produced in E.Coli is a two chain, non-glycosylated polypeptide chain containing 51 amino acids and having a molecular mass of 5807 Dalton. Insulin is purified by proprietary chromatographic techniques. | |||
Source | Escherichia Coli. | |||
Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | |||
Formulation | The protein was lyophilized from a concentrated (1mg/ml) solution with no additives. | |||
Solubility | It is recommended to reconstitute the lyophilized Insulin in sterile 0.005N HCl not more than 1 mg/ml. | |||
Stability | Lyophilized Insulin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Insulin should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |||
Purity | Greater than 98.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |||
Biological Activity | The Biological Activity was determined to be 28 units/mg. | |||
References | Title: PI3K integrates the effects of insulin and leptin on large-conductance Ca2+-activated K+ channels in neuropeptide Y neurons of the hypothalamic arcuate nucleus Publication: American Journal of Physiology-Endocrinology and Metabolism 298.2 (2010): E193-E201. Link: http://ajpendo.physiology.org/content/298/2/E193.shorty | |||
Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. | |||
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