货号: | PL0305757 |
抗体名: | 白细胞共同抗原抗体 |
抗体英文名: | CD45/B220 Antibody |
靶点: | CD45/B220 |
浓度: | 1mg/ml |
应用范围: | WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500 FC:1:100-500 |
宿主: | Rabbit |
适应物种: | Mo |
标记物: | 无标记(PLlabs可供应生物素、酶、荧光素标记的抗体) |
克隆性: | 否 |
保存条件: | 保存于-20℃ |
形态: | 液态 |
亚型: | Rabbit Polyclonal IgG |
免疫原: | Peptide derived from mouse CD45/B220. |
规格: | 0.1ml |
CD45/B220 Antibody
Cat#:PL0305757
Isotype:Rabbit Polyclonal IgG
Immunogen:Peptide derived from mouse CD45/B220.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling.
Alternate Names:
B220; CD45; cd45 antigen; GP180; LCA; Leukocyte common antigen; LY5; Protein tyrosine phosphatase receptor type C; Protein tyrosine phosphatase receptor type c polypeptide; protein tyrosine phosphatase, receptor type, C; Receptor-type tyrosine-protein phosphatase C; PTPRC; PTPRC_HUMAN; SCID due to PTPRC deficiency; T200; T200 glycoprotein; T200 leukocyte common antigen; Human homolog of severe combined immunodeficiency due to PTPRC deficiency.
Specificity Reaction:Mo
Application Notes:WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500 FC:1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素(FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体,欢迎大家咨询订购。
温馨提示:不可用于临床治疗。