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AddexBio PC-3 cells (前列腺癌等级四
L-02人正常肝细胞
ATCC细胞株、菌株、细菌
通过黄浦区市场监管局认证 
石墨化炭黑/氨基复合
乙酰辅酶A
胆碱氧化酶| 货号： | ab120488 |
| 英文名： | Z-D(OMe)E(OMe)VD(OMe)-FMK |
| 保质期： | 12个月 |
| 保存条件： | Store at -20°C |
| 规格： | 1 mg |
概述
- 产品名称
Z-D(OMe)E(OMe)VD(OMe)-FMK - 描述
Cell permeable caspase-3 inhibitor - 别名
- Caspase-3 Inhibitor
- Z-DEVD-FMK (cell permeable)
- 生物学描述
A potent, cell-permeable, and irreversible inhibitor of caspase-3. Also inhibits caspase-6, caspase-7, caspase-8, and caspase-10. Once in the cell, endogenous esterase activity hydrolyzes the methyl groups to form the biologically active form. Therefore, when using with isolated, purified or recombinant caspase enzymes, pre-treatment with an esterase is required. - 纯度
> 90%
性能
- 分子量
668.67 - 化学结构
- 分子式
C30H41FN4O12 - 序列
DEVD (Modifications: N-terminal benzyloxycarbonyl; C-terminal FMK; Asp-1 = Asp(OMe); Glu-2 = Glu(OMe); Asp-4 = Asp(OMe)) - PubChem识别号
16760394 - 存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. - 溶解度概述
Soluble in DMSO to 20 mM - 处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- SMILES
FCC(=O)[C@H](CC(=O)OC)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)OC)NC(=O)[C@H](CC(=O)OC)NC(=O)OCc1ccccc1)C(C)C - 来源
Synthetic
温馨提示：不可用于临床治疗。
