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L-胱氨酸
植物激素脱落酸（ABA ）ELISA试剂盒
Human progesterone receptor,PGR ELI
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凝血因子V缺乏血浆（F
凝血因子XI缺乏血浆（
凝血因子X缺乏血浆（F
凝血因子IX缺乏血浆（
血小板诱导剂：瑞斯托
血小板诱导剂：胶原，
冻干血小板，(瑞斯托
血小板诱导剂：二磷酸| 货号： | CU1001a |
| 样本： | 30 μl |
| 应用： | 血浆、细胞培养上清液 |
| 检测方法： | 发色底物法 |
| 检测限： | 0.1 IU/ml |
| 供应商： | AssayPro |
| 数量： | 大量 |
| 规格： | 96 wells |
AssaySense Human uPA Chromogenic Activity Assay Kit
尿激酶发色底物法活性试剂盒-直接法
Introduction 尿激酶发色底物法活性试剂盒-直接法
Urokinase-type plasminogen activator (uPA) is a highly restricted serine protease that converts the zymogen plasminogen to active plasmin, a broad-spectrum serine proteinase capable of degrading most of the major protein components of the extracellular matrix. Binding of uPA to its receptor and subsequent uPA mediated pericellular proteolysis are involved in many process including cell migration and tissue remodeling in angiogenesis, atherogenesis, tumor cell metastasis, and ovulation (1, 2). High level of uPA is a poor prognostic marker for aggressive breast cancer, aggressive prostate cancer, bladder cancer and gastric cancer (3, 4, 5).
Principle of Assay
The AngioSense Human uPA Chromogenic Activity Assay Kit is developed to determine human uPA activity in plasma and cell culture supernatants. The amidolytic activity of uPA is quantitated using a highly specific uPA substrate releasing a (pNA) chromophore. The change in absorbance of the pNA at 405 nm is directly proportional to the uPA enzymatic activity.
温馨提示：不可用于临床治疗。
