Synonyms : PDL1; Programmed Cell Death 1 Ligand Protein 1; PDCD1 Ligand 1; B7-H1Host : CHO cellSequence : The extracellular domain of human CD274[B7-H1](NP_054862.1)(Phe19-Arg238) is fused to the N-terminus of the Fc region of a mutant human IgG1.Molecular Mass : 54 KDa (monomer)Non-lytic : Acts as a long lasting fusion protein which only binds to the receptor. Mutations to the complement (C1q) and FcgRI binding sites of the IgGs Fc fragment render the fusion proteins incapable of antibody directed cytotoxicity(ADCC) and complement directed cytotoxicity (CDC).Purity : >98%，by SDS-PAGE under reducing conditions. Endotoxin Content : <0.06 EU/μg as determined by LAL test.Activity : Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes.Formulation : Lyophilized from 0.2μm-filtered solution in PBS.Reconstitution : Reconstitute at 100μg/ml in sterile PBS.Use / Stability :Stable for at least 1 year after receipt when stored at -20℃. Working aliquots are stable for up to 3 months when stored at -20℃.Avoid freeze/thaw cycles.
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