Synonyms : Interleukin-15Host : CHO cellSequence : The extracellular domain of human IL-15(NP_751914.1)(Asn49-Ser162)including mutations at Q149D and Q156D is fused to the N-terminus of the Fc region of human IgG1.Molecular Mass : 41 KDa (monomer)Purity : >98%，by SDS-PAGE under reducing conditions. Endotoxin Content : <0.06 EU/μg as determined by LAL test.Activity : This mutant IL-15/Fc fusion protein specifically binds to the IL-15R, competitively inhibits IL-15-triggered cell proliferation, promotes transplant tolerance, does not activate the STAT -signaling pathway, and exerts a prolonged circulating half-life caused by the modified Fc domain. Formulation : Lyophilized from 0.2μm-filtered solution in PBS.Reconstitution : Reconstitute at 100μg/ml in sterile PBS.Use / Stability :Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.Avoid freeze/thaw cycles.
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