动物颅脑损伤仪VCU

VCU动物颅脑损伤仪

VCU动物颅脑损伤仪可以分为细胞颅脑损伤仪(CIC)，电子颅脑损伤仪(eCCI)及液压颅脑损伤仪(FPI)，這三种产品己广泛应用于世界范围内的颅脑创伤研究中心，是目前唯一的颅脑创伤模型制作的金标准。

电子颅脑损伤仪(eCCI)

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细胞颅脑损伤仪(CIC)       ，   

液压颅脑损伤仪(FPI)

液压颅脑损伤仪(FPI)

液压颅脑损伤仪(FPI)是由VCU 大学所制作设計的，针对神经创伤机制研究，成为全球研究神经创伤广泛使用的仪器，基本的组件是採取最先进的power coating process技术，铝制部分的组件都已经电度以避免氧化且可以长久使用。

The FPI is constructed with a sturdy aluminum frame and the basic structure is finished with a state-of-the-art powder coating process. The balance of the aluminum components are anodized to prevent oxidation and guarantee longevity.

FPI assembly includes the base pendulum mast, graduated protractor, ball bearing-enhanced impact hammer assembly, acrylic fluid cylinder and bracketry, transducer housing, transfer tube and a digital transducer. The device is completed with a self-calibrating Trauma Inducer Pressure Inducer Amplifier.

电子颅脑损伤仪(eCCI)是由VCU 大学所制作设计的，針对颅脑创伤机制研究。

电子颅脑损伤仪(eCCI)的组件有: sturdy aluminum frame, animal platform, controller and impactor head。Animal plateform可以和各种的立体定位仪搭配。是藉由controller來控制撞击的速度，撞击头的组件部份有含感应器，可以決定速率、撞击深度及撞击位置。

The eCCI is constructed with a sturdy aluminum frame to maximize rigidity, thereby ensuring impact accuracy. The support base, animal platform and impactor head are anodized to prevent oxidation and assure equipment longevity.  

Product assembly includes the base and support frame, and adjustable animal positioner with an aluminum animal platform to be used in conjunction with a variety of stereotactic mounts. This model utilizes the enhanced linier motor driven impactor and controller. The enhanced impact head also houses a photo-optic sensor to determine velocity, impact depth and dwell, and is extremely reproducible.

细胞颅脑损伤仪(CIC)

细胞损伤控制仪(CI採取电子式控制，適合morphologic、病理理及培养组织损伤后的机制、形态学、病理性。细胞损伤控制仪是针对Flexcell Int’l corp具有专利的tissue culture system。细胞损伤控制仪平均把压缩气体送到每个culture wells，以造成培养组织牵张性的损伤，损伤的严重程度是依据气体在密闭的culture well进出的量，细胞损伤控制仪(CIC)是可以搭配Flex ® 29.45cm2 culturing trays I (针对VCU早期的细胞损伤控制仪)和BioFlex® 57.75cm2 culturing trays。因为根据所採用的细胞种类、损伤的程度、培养的狀況，受损后的细胞或许会因为上述因素死掉或要修护，所以VCU的细胞损伤控制仪(CIC)很適合应用在下列领域:细胞受损、修护，死亡，药物介入的反应。

The Cell Injury Controller II is an electronically controlled pneumatic device that allows the study of morphologic, physiologic and biochemical responses of tissue-cultured cells to trauma.

Depending on the cell type, the degree of injury and the culture conditions, the injured cells may die or repair. Therefore, the system can be employed to study the responses to trauma, including cell injury, repair, death or pharmacologic intervention.

The CIC II has been designed for use with a patented, commercially available tissue culture system from Flexcell International Corp. in Hillsborough, N.C. Tissue cultures are grown in culturing wells with stretchable Silastic® membrane bottoms. The CIC II regulates the flow of compressed gas to rapidly pressurize individual culture wells, causing a radial stretch injury to the culture. Injury severity is determined by controlling the flow of gas in and out of the sealed culture well and the peak pressure is captured to provide an accurate indicator of radial stretch.

The CIC II accepts both the Flex I® 29.45cm2 culturing trays, which were used with the earlier CIC Model 94A, and the BioFlex® 57.75cm2 culturing trays.