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人OP酶联免疫检测试剂| 货号： | ABS 006-240 |
| 抗体名： | Anti-Pregnancy associated plasma protein A (human, PAPP-A) |
| 抗体英文名： | Anti-Pregnancy associated plasma protein A (human, PAPP-A) |
| 靶点： | 见官方网站 |
| 浓度： | 1 mg/ml |
| 应用范围： | ELISA, WB, IHC |
| 宿主： | Human |
| 供应商： | 上海泽叶生物科技有限公司 |
| 数量： | 30 |
| 级别： | 见官方网站 |
| 目录编号： | ABS 006-240 |
| 抗原来源： | 见官方网站 |
| 保质期： | 1年 |
| 适应物种： | 见官方网站 |
| 标记物： | 见官方网站 |
| 克隆性： | 否 |
| 保存条件： | -20ºC |
| 形态： | 冻干粉或液体 |
| 亚型： | 见官方网站 |
| 免疫原： | 见官方网站 |
| 规格： | 200ug |
Anti-Pregnancy associated plasma protein A (human, PAPP-A)
Bioporto是一家体外诊断公司，专业为临床和科研提供一系列诊断试剂盒和抗体。其领先的产品组合包括了用于急性肾功能损伤诊断用的NGAL以及其它疾病检测用抗体。官方网站：www.bioporto.com
- Cat. No.
- ABS 006-240
- Product name
- Anti-Pregnancy associated plasma protein A (human, PAPP-A)
- Description
-
Mouse monoclonal antibody
- Specificity
-
ABS 006-24 is specific for native human PAPP-A. Heat and SDS denatured PAPP-A is also recognized, but not acid treated PAPP-A .
- Immunogen
-
Purified human PAPP-A
- Application
- ELISA, WB, IHC
- Species reactivity (positive)
- Human
- Species reactivity (negative)
- Not determined
- Subclass
-
IgG1/k
- Gene ID
- 5069
- Clone number
- PAPP A 1-24
- Epitope
-
The epitope of ABS 006-24 is different from BTE 004-09 and ABS 006-01. The epitope is located on the PAPP-A subunit of the heterotetramer.
- Content
-
Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
- Purification
- Protein-A purified
- Form
- Liquid
- Solvent
- 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
- Storage
- 4-8ºC without exposure to light. No precautions necessary during handling.
- Target
-
Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterotetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down’s syndrome (trisomy 21).
- Application 1
-
ELISA
BTE 004-09 as coating antibody and biotinylated ABS 006-24 as detection antibody is a good combination for sandwich ELISA. - Application 2
-
WB
ABS 006-24 only detecs unreduced PAPP-A in Western Blotting. - Application 3
-
IHC
ABS 006-24 gives the strongest singal in IHC compared to ABS 006-01 and BTE 004-09.
Immunohistochemical staining of a formalin-fixed, paraffin-embedded placental tissue with ABS 006-24
