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人OP酶联免疫检测试剂| 货号： | HYB 131-102 |
| 抗体名： | Anti-MBL (human) |
| 抗体英文名： | Anti-MBL (human) |
| 靶点： | 见官方网站 |
| 浓度： | 1 mg/ml |
| 应用范围： | ELISA, WB |
| 宿主： | Human |
| 供应商： | 上海泽叶生物科技有限公司 |
| 数量： | 30 |
| 级别： | 见官方网站 |
| 目录编号： | HYB 131-102 |
| 抗原来源： | 见官方网站 |
| 保质期： | 1年 |
| 适应物种： | 见官方网站 |
| 标记物： | 见官方网站 |
| 克隆性： | 否 |
| 保存条件： | -20ºC |
| 形态： | 冻干粉或液体 |
| 亚型： | 见官方网站 |
| 免疫原： | 见官方网站 |
| 规格： | 200ug |
Anti-MBL (human)
Bioporto是一家体外诊断公司，专业为临床和科研提供一系列诊断试剂盒和抗体。其领先的产品组合包括了用于急性肾功能损伤诊断用的NGAL以及其它疾病检测用抗体。官方网站：www.bioporto.com
- Cat. No.
- HYB 131-102
- Product name
- Anti-MBL (human)
- Description
-
Mouse monoclonal antibody
- Specificity
-
HYB 131-10 is specific for MBL (mannan-binding lectin) from human serum or plasma.
- Immunogen
-
MBL purified from human donor plasma.
- Application
- ELISA, WB
- Species reactivity (positive)
- Human
- Species reactivity (negative)
- Not determined
- Subclass
-
IgG1/k
- Gene ID
- 4153
- Clone number
- 1E2
- Epitope
-
The epitope is thought to be on the carbohydrate recognition domain and differs from that of HYB 131-01 and HYB 131-11.
- Content
-
Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
- Purification
- Protein-A purified
- Form
- Liquid
- Solvent
- 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
- Storage
- 4-8ºC without exposure to light. No precautions necessary during handling.
- Target
-
Mannan-binding lectin (MBL), also called mannose-binding lectin or protein, belongs to the C-type family of collectins, showing calcium-dependent binding to certain sugars (1). It consists of oligomers of triple-chain subunits and its binding and complement activating activities depend on its normal oligomerization. On binding to mannan-like microbial surface carbohydrates, MBL activates the complement system by means of its own lectin pathway, depending on the MBL-associated serine proteases (MASPs). Because of the presence of different structural and promoter alleles in the population, 12% or more of the population have low concentrations (<50ng/mL) of normally oligomerized, functional MBL in plasma or serum.
- Application 1
-
ELISA
HYB 131-10 reacts strongly with MBL. Strong reaction is seen in ELISA with MBL coated directly onto the microtiter well. In Western blotting HYB 131-10 reacts with human MBL in both its oligomerized state and as single protein chain of 26 kDa. HYB 131-10 can be used to measure MBL in plasma or serum but is not specific for oligomerized MBL when used in combination with itself or other MBL antibodies(1). - Application 2
-
WB
HYB 131-10 can be used in Western blotting.
