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MicroVue CICP EIA*| 货号： | AK-238 |
| 抗体名： | Neurotrophin Receptor Antibody Explorer Kit |
| 抗体英文名： | Neurotrophin Receptor Antibody Explorer Kit |
| 靶点： | 见官方网站 |
| 浓度： | 见官方网站 |
| 应用范围： | 见官方网站 |
| 宿主： | 见说明书 |
| 供应商： | 上海信裕生物科技有限公司 |
| 数量： | 大量 |
| 级别： | 高 |
| 目录编号： | AK-238 |
| 抗原来源： | 见说明书 |
| 保质期： | 6个月 |
| 适应物种： | 见官方网站 |
| 标记物： | 见官方网站 |
| 克隆性： | 否 |
| 保存条件： | -20°C |
| 形态： | 液体或冻干粉 |
| 亚型： | 见官方网站 |
| 免疫原： | 见官方网站 |
| 规格： | 12 Vials |
Neurotrophin Receptor Antibody Explorer Kit
A Screening Package of Neurotrophin Receptor Antibodies Economically PricedCat #: AK-238
12 Vials
Alomone Labs is pleased to offer the Neurotrophin Receptor Antibody Explorer Kit (#AK-238). This Explorer Kit includes neurotrophin receptor antibodies with their respective peptide control antigen. An ideal tool for screening purposes.
- Compounds
- Scientific Background
- Related Products
| Product Name | Cat # | Size |
|---|---|---|
Anti-p75NTR (intracellular) | ANT-011 | 1 x 50 µl |
Anti-p75NTR (extracellular) | ANT-007 | 1 x 50 µl |
Anti-Sortilin (extracellular) | ANT-009 | 1 x 50 µl |
Anti-TrkA (extracellular) | ANT-018 | 1 x 50 µl |
Anti-TrkB (extracellular) | ANT-019 | 1 x 50 µl |
Anti-TrkC (extracellular) | ANT-020 | 1 x 50 µl |
Neurotrophin Receptor Antibody Explorer KitScientific Background
NGF was the first neurotrophin to be discovered, more than 50 years ago. Three other proteins have been added to the list: BDNF, NT-3 and NT-4 (NT-4/5). These neurotrophins bind two groups of receptors. The p75NTR receptor is common to all four neurotrophins and is a member of the tumor necrosis factor receptor family. The tropomyosin-related kinase (Trk) receptors are receptor tyrosine kinases (RTKs) and three receptors form this family: TrkA, TrkB, and TrkC1.
As mentioned above, the p75NTR receptor binds to all neurotrophins with similar affinities while the Trk receptors are the ones to display the selectivity for the neurotrophins. TrkA is activated by NGF binding, TrkB by that of BDNF and NT-4, while TrkC is stimulated by the binding of NT-3 1.
References
- Webster, N.J. et al. (2008) BMC Neurosci. 9, S1.
