激酶抑制剂分子库

产品描述及优势

• 273种激酶抑制剂的独特集合，可用于高通量筛选和高内涵筛选 • 通过前期临床研究和临床实验，生物活性和安全性得到验证 • 其中一些激酶抑制剂已得到FDA批准 • 作用于激酶，如RTKs, PI3K, Aurora激酶, CDK和MEK • 大部分为ATP竞争性抑制剂 • 结构多样，药效显著，可渗透细胞 • 具有充分详细的结构说明，IC50值，及客户反馈资料 • NMR和HPLC技术保证产品高纯度

 

 

产品详细信息

配制:	273种激酶抑制剂预溶在DMSO溶液中
96-孔板:	96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
稳定性:	3月 -20°C 溶于DMSO 6月 -80°C 溶于DMSO
发货:	蓝冰物流
包装:	惰性气体

 

 

 

Product Details:

Formulation

A collection of 273 kinase inhibitors supplied as lyophilized powder or pre-dissolved DMSO solutions

Container (Optional)

A: Deep-well 96-well plate

B: 96-well racks with TrakMate screwtop tubes & caps

Stability

2 weeks | 4°C | in DMSO

3 months | ﹣20°C | in DMSO

6 months | ﹣80°C | in DMSO

Shipping

Blue ice

Packaged under inert gas

Yes

Plate layout: L1200-01

1

2

3

4

5

6

7

8

9

10

11

12

a

Empty

Linifanib (ABT-869)

Cediranib (AZD2171)

Imatinib Mesylate

Rapamycin (Sirolimus)

Enzastaurin (LY317615)

SB 216763

Linsitinib (OSI-906)

GDC-0879

GSK690693

AT9283

Empty

b

Empty

Axitinib

Dovitinib (TKI-258)

Lapatinib Ditosylate (Tykerb)

Sorafenib (Nexavar)

BMS-599626 (AC480)

SB 203580

KU-55933

LY294002

JNJ-38877605

Brivanib alaninate (BMS-582664)

Empty

c

Empty

Saracatinib (AZD0530)

CI-1033 (Canertinib)

Motesanib Diphosphate (AMG-706)

Sunitinib Malate (Sutent)

Masitinib (AB1010)

SB 202190

GSK1904529A

OSU-03012

PD 0332991 (Palbociclib) HCl

AG-490

Empty

d

Empty

AZD6244 (Selumetinib)

CI-1040 (PD184352)

Nilotinib (AMN-107)

Tandutinib (MLN518)

GDC-0941

MK-2206 2HCl

PF-04217903

Danusertib (PHA-739358)

Triciribine (Triciribine phosphate)

SNS-032 (BMS-387032)

Empty

e

Empty

BEZ235 (NVP-BEZ235)

Dasatinib (BMS-354825)

Pazopanib HCl

Temsirolimus (Torisel)

SB 431542

PD153035 HCl

MLN8054

TAE684 (NVP-TAE684)

XL147

Barasertib (AZD1152-HQPA)

Empty

f

Empty

BIBF1120 (Vargatef)

Deforolimus (Ridaforolimus)

PD0325901

Vandetanib (Zactima)

Crizotinib (PF-02341066)

SU11274

Vatalanib 2HCl (PTK787)

BI 2536

XL-184 (Cabozantinib)

PLX-4720

Empty

g

Empty

Afatinib (BIBW2992)

Erlotinib HCl

Empty

VX-680 (MK-0457, Tozasertib)

PHA-665752

Brivanib (BMS-540215)

U0126-EtOH

Foretinib (GSK1363089, XL880)

Everolimus (RAD001)

Roscovitine (Seliciclib, CYC202)

Empty

h

Empty

Bosutinib (SKI-606)

Gefitinib (Iressa)

PI-103

Y-27632 2HCl

ZSTK474

NVP-ADW742

ZM-447439

SGX-523

MLN8237 (Alisertib)

SNS-314

Empty

Plate layout: L1200-02

1

2

3

4

5

6

7

8

9

10

11

12

a

Empty

E7080 (Lenvatinib)

WZ8040

AG-1024

BX-912

Pelitinib (EKB-569)

TSU-68 (SU6668)

LY2228820

AZD7762

PD318088

Neratinib (HKI-272)

Empty

b

Empty

CP-724714

ENMD-2076

Amuvatinib (MP-470)

AMG-208

AS-605240

AS703026 (pimasertib)

CCT129202

R406 (free base)

KU-60019

KW 2449

Empty

c

Empty

TGX-221

PIK-90

JNJ-7706621

TG100-115

Staurosporine

SB 525334

XL765

CP 673451

BS-181 HCl

Empty

Empty

d

Empty

WZ3146

PIK-75

PD173074

GSK1059615

Aurora A Inhibitor I

HMN-214

AT7519

AZD8055

BIRB 796 (Doramapimod)

LY2784544

Empty

e

Empty

CYC116

Tivozanib (AV-951)

WYE-354

MGCD-265

PHA-680632

AEE788 (NVP-AEE788)

Quizartinib (AC220)

PHT-427

Tie2 kinase inhibitor

BGJ398 (NVP-BGJ398)

Empty

f

Empty

WZ4002

YM201636

Vemurafenib (PLX4032)

ON-01910

Thiazovivin

PHA-793887

Hesperadin

KRN 633

TWS119

AST-1306

Empty

g

Empty

PD98059

OSI-930

IC-87114

Ki8751

SP600125

PIK-93

BIX 02188

AT7867

BMS-265246

AZD8931

Empty

h

Empty

Regorafenib (BAY 73-4506)

Ku-0063794

BX-795

Ruxolitinib (INCB018424)

Empty

Ponatinib (AP24534)

BIX 02189

BMS 777607

AZD8330

GSK461364

Empty

Plate layout: L1200-03

1

2

3

4

5

6

7

8

9

10

11

12

a

Empty

R406

Mubritinib (TAK 165)

BI6727 (Volasertib)

Phenformin HCl

PF-05212384 (PKI-587)

A-674563

CHIR-124

TAK-901

Crenolanib (CP-868596)

CHIR-98014

Empty

b

Empty

Raf265 derivative

PP242

Palomid 529

TAK-733

DCC-2036 (Rebastinib)

AS-252424

NVP-BSK805

AMG 900

Empty

AZ628

Empty

c

Empty

BMS 794833

Cyt387

WP1130

LDN193189

CCT128930

PF-00562271

WAY-600

ZM 336372

TG101348 (SAR302503)

AMG458

Empty

d

Empty

NVP-BHG712

SB590885

BKM120 (NVP-BKM120)

AZD5438

A66

GSK1120212 (Trametinib)

TG101209

PF-03814735

PKI-402

NVP-BGT226

Empty

e

Empty

OSI-420

Apatinib (YN968D1)

CX-4945 (Silmitasertib)

PP-121

NU7441 (KU-57788)

Flavopiridol HCl

GDC-0980 (RG7422)

PH-797804

GSK1070916

Milciclib (PHA-848125)

Empty

f

Empty

R935788 (Fostamatinib disodium, R788 disodium)

CAL-101 (GS-1101)

Indirubin

OSI-027

GSK2126458

PCI-32765 (Ibrutinib)

A-769662

Dacomitinib (PF299804,PF-00299804)

PHA-767491

Arry-380

Empty

g

Empty

PIK-293

PIK-294

Quercetin (Sophoretin)

R788 (Fostamatinib)

WYE-125132

AS-604850

KX2-391

AG-1478 (Tyrphostin AG-1478)

PF-04691502

ARQ 197 (Tivantinib)

Empty

h

Empty

AZ 960

Telatinib (BAY 57-9352)

Imatinib (Gleevec)

LY2603618 (IC-83)

WYE-687

CAY10505

GSK1838705A

SB 415286

CCT137690

ARRY334543

Empty

Plate layout: L1200-04

1

2

3

4

5

6

7

8

9

10

11

12

a

Empty

Wortmannin

AZD2014

Dabrafenib (GSK2118436)

TPCA-1

WHI-P154

Empty

Empty

Empty

Empty

Empty

Empty

b

Empty

NVP-BVU972

TAK-285

GDC-0068

Desmethyl Erlotinib (CP-473420)

TG 100713

Empty

Empty

Empty

Empty

Empty

Empty

c

Empty

CH5424802

INCB28060

INK 128 (MLN0128)

Torin 1

Piceatannol

Empty

Empty

Empty

Empty

Empty

Empty

d

Empty

3-Methyladenine

Tofacitinib (CP-690550, Tasocitinib)

BYL719

SAR131675

Tofacitinib citrate (CP-690550 citrate)

Empty

Empty

Empty

Empty

Empty

Empty

e

Empty

Dinaciclib (SCH727965)

Sotrastaurin (AEB071)

Tyrphostin AG 879 (AG 879)

Semaxanib (SU5416)

VX-702

Empty

Empty

Empty

Empty

Empty

Empty

f

Empty

Dovitinib Dilactic acid (TKI258 Dilactic acid)

WP1066

Torin 2

Baricitinib (LY3009104,incb28050)

Empty

Empty

Empty

Empty

Empty

Empty

Empty

g

Empty

MK-5108 (VX-689)

AZD4547

NVP-TAE226

Golvatinib (E7050)

Empty

Empty

Empty

Empty

Empty

Empty

Empty

h

Empty

MK-2461

CEP33779

Tideglusib

IMD 0354

Empty

Empty

Empty

Empty

Empty

Empty

Empty