货号: | LA3-C52A0 |
供应商: | ACROBiosystems |
数量: | In Stock |
英文名: | Cynomolgus LAG-3 / CD223 Protein, Mouse IgG2a Fc Tag |
规格: | 100ug |
Less than 1.0 EU per μg by the LAL method.
纯度:
>85% as determined by SDS-PAGE.
活性:
Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus LAG-3, mouse IgG2a Fc tag (Catalog # LA3-C52A0) at 2 μg/mL (100 μL/well) can bind Anti-LAG3 MAb,Human IgG1 with a linear range of 3-20 ng/mL.
产品背景:
Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
产品描述:
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 73.7 kDa. The protein migrates as 78-92 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
SDS-PAGE
Cynomolgus LAG-3 / CD223, Mouse IgG2a Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 85%.
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