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Angiotensin I, human
PeproTechGMP级别重组人TPO 100ug
IL27 / Interleukin-27 Protein (His
[VIP第1年] 指数:2
通过北京市工商行政管理局北京经济技术开发区分局认证 
重组人CD36 蛋白
PF Pro CHO-1
CDPro CHO-2 Medium, 
Follistatin /FST| 货号： | CSR-C5252 |
| 供应商： | ACROBiosystems |
| 数量： | In Stock |
| 英文名： | Cynomolgus M-CSF R / CSF1R / CD115 Protein, Fc Tag |
| 规格： | 100ug/1mg |
Less than 1.0 EU per μg by the LAL method.
纯度:
>95% as determined by SDS-PAGE.
活性:
产品背景:
Colony stimulating factor 1 receptor (CSF1R) is also known as macrophage colony-stimulating factor receptor (M-CSFR), CD115 Cluster of Differentiation 115 (CD115), C-FMS, CSFR, FIM2, FMS, and is a member of the typeⅢ subfamily of receptor tyrosine kinases (RTKs). CSF1R is a receptor for a cytokine called colony stimulating factor 1, The protein encoded by the CSFR1 gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most, if not all, of the biological effects of this cytokine. Ligand binding activates CSFR1 through a process of oligomerization and transphosphorylation . Mutations in CSF1R are associated with chronic myelomonocytic leukemia and type M4 acute myeloblastic leukemia. Increased levels of CSF1R1 are found in microglia in Alzheimer's disease and after brain injuries. The increased receptor expression causes microglia to become more active. Both CSF1R, and its ligand colony stimulating factor 1 play an important role in the development of the mammary gland and may be involved in the process of mammary gland carcinogenesis.
产品描述:
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 81.9 kDa. As a result of glycosylation, the protein migrates as 110-125 kDa under reducing (R) condition, and 200- 240 kDa under non-reducing (NR) condition (SDS-PAGE).
SDS-PAGE
Cynomolgus M-CSF R, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
温馨提示：不可用于临床治疗。
