Rabbit Anti-Cecropin antibody
产品编号 | hz-2080R |
英文名称 | Cecropin |
中文名称 | 抗菌肽/天蚕素抗体 |
产品类型 | 植物抗体 |
研究领域 | 细菌及病毒 植物 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Hyalophora cecropia |
产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 4kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide from Hyalophora cecropia Cecropin:1-37/41 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
PubMed | PubMed |
产品介绍 | background: Cecropins are antimicrobial peptides.They were first isolated from the hemolymph of Hyalophora cecropia, from whence the term cecropin was derived. Cecropins lyse bacterial cell membranes; they also inhibit proline uptake and cause leaky membranes. Cecropins constitute a main part of the cell-free immunity of insects. Cecropins are small proteins of about 31 - 37 amino acid residues active against both Gram-positive and Gram-negative bacteria. Cecropins isolated from insects other than Hyalophora cecropia (Cecropia moth) have been given various names; bactericidin, lepidopteran, sarcotoxin, etc. All of these peptides are structurally related. Cecropin P1, an intestinal antibacterial peptide from Sus scrofa (Pig), also belongs to this family. Cecropin family also consists Cecropin A and Cecropin B. Function: Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria. Subcellular Location: Secreted. Post-translational modifications: A protein with the same sequence as cecropin A, but lacking the carboxyl blocking group, has been isolated and called cecropin C (PubMed:7140755). Similarity: Belongs to the cecropin family. SWISS: N/A Gene ID: N/A Database links: Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Cecropin抗菌肽又称天蚕素,具有抗菌、抗病毒、抗肿瘤等活性,因其水溶性好,耐高温,是一种比较理想的抗生素代用品;尤其是其主要抑菌机制,可破坏细胞膜的稳定性,不易产生耐药性。 抗菌肽一般是小肽,可以被动物完全消化,不存在残留性的问题,所以,抗菌肽无论是作为饲料添加剂,兽药还是人药,都有理论上的研究价值和生产中的实际意义。 |