Anti-MAN2A2抗体
产品编号 | YB-18646R |
英文名称 | MAN2A2 |
中文名称 | α-甘露糖苷酶2x抗体 |
别 名 | 3-1; 6-alpha-mannosidase; Alpha-mannosidase 2x; Alpha-mannosidase IIx; MA2A2_HUMAN; MAN IIx; MAN2A2; MANA2X; Mannosidase alpha class 2A member 2; Mannosyl-oligosaccharide 1; Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase; MX. |
规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
说 明 书 | 100ul 200ul |
研究领域 | 细胞生物 新陈代谢 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, |
产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 131kDa |
细胞定位 | 细胞浆 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MAN2A2:1-100/1150 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
PubMed | PubMed |
产品介绍 | background: MAN2A2 is a single-pass type II membrane protein that localizes to the cisternae of the golgi and is involved in protein modification pathways. More specifically, MAN2A1 uses zinc as a cofactor to catalyze the first committed step in the formation of N-glycans, namely the hydrolysis of the terminal alpha-D-mannose residues in the oligosaccharide Man5(GlcNAc)3. Function: Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway. Subcellular Location: Golgi apparatus membrane. Similarity: Belongs to the glycosyl hydrolase 38 family. SWISS: P49641 Gene ID: 4122 Database links: Entrez Gene: 4122 Human Entrez Gene: 140481 Mouse Omim: 600988 Human SwissProt: P49641 Human SwissProt: Q8BRK9 Mouse Unigene: 116459 Human Unigene: 269245 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品图片 | Sample: LOVO(Human) Cell Lysate at 30 ug FHC(Human) Cell Lysate at 30 ug Primary: Anti-MAN2A2 (bs-18646R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 131 kD Observed band size: 131 kD |