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Anti-MACROD2/C20orf133抗体

产品价格: ¥1380.00

最小起订量:暂无 可售数量:暂无

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全国
有效期至:
长期有效
最后更新:
2021-05-28 01:30:05
浏览次数:
201

产品详情

品牌名称:
Ybscience

 Anti-MACROD2/C20orf133抗体

产品编号 YB-18603R
英文名称 MACROD2/C20orf133
中文名称 20号染色体开放阅读框133抗体
别    名 C20orf133; MACD2_HUMAN; MACRO domain containing 2; MACRO domain-containing protein 2; macrod2; O-acetyl-ADP-ribose deacetylase MACROD2.  
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  信号转导  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MACROD2/C20orf133:1-100/448 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background: MACROD2 (MACRO Domain Containing 2) is a Protein Coding gene. Diseases associated with MACROD2 include autism spectrum disorder and pervasive developmental disorder. GO annotations related to this gene include hydrolase activity, acting on glycosyl bonds and deacetylase activity. An important paralog of this gene is MACROD1. Function: Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Subunit: Interacts with ADP-ribosylated PARP1. Subcellular Location: Nucleus. Similarity: Contains 1 Macro domain. SWISS: A1Z1Q3 Gene ID: 140733 Database links:

Entrez Gene: 140733 Human

Entrez Gene: 72899 Mouse

SwissProt: A1Z1Q3 Human

SwissProt: Q3UYG8 Mouse

Unigene: 661576 Human

Unigene: 229466 Mouse

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.   
产品图片
Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (C20orf133) Polyclonal Antibody, Unconjugated (bs-18603R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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