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Anti-MACROD2/C20orf1Anti-Cardiodilatin-related peptide抗体
| 产品编号 | YB-5225R |
| 英文名称 | Cardiodilatin-related peptide |
| 中文名称 | 心舒血管素相关肽抗体 |
| 别 名 | Prepronatriodilatin; ANF_HUMAN; ANF; Atrial natriuretic factor; Cardiodilatin related peptide; CDD ANF; CDP; PND; Prepronatriodilatin; Nppa; Natriuretic peptides A; Atrial natriuretic peptide; CDD-ANF; Cardiodilatin-related peptide; ANP. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 3/17kDa |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Cardiodilatin-related peptide:21-100/153 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq, Sep 2009]. Function: Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. Subunit: Interacts with NPR1. Subcellular Location: Secreted. Post-translational modifications: Cleaved by CORIN upon secretion to produce the functional hormone. DISEASE: Atrial fibrillation, familial, 6 (ATFB6) [MIM:612201]: A familial form of atrial fibrillation, a common sustained cardiac rhythm disturbance. Atrial fibrillation is characterized by disorganized atrial electrical activity and ineffective atrial contraction promoting blood stasis in the atria and reduces ventricular filling. It can result in palpitations, syncope, thromboembolic stroke, and congestive heart failure. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the natriuretic peptide family. SWISS: P01160 Gene ID: 4878 Database links: Entrez Gene: 4878 Human Entrez Gene: 608289 Dog Entrez Gene: 230899 Mouse Omim: 108780 Human SwissProt: P07499 Dog SwissProt: P01160 Human SwissProt: P05125 Mouse Unigene: 75640 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品图片 |  Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti- Cardiodilatin-related peptide (bs-5225R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 3/17 kD Observed band size: 17 kD |
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