分子量:42.6 kDa纯度:>95% as determined by SDS-PAGE.内毒素:Less than 1.0 EU per μg of the Mouse ROR1, His Tag by the LAL method.Buffer:PBS, pH7.4生物活性:产品特性:Mouse ROR1, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 42.6 kDa. The predicted N-terminus is Gln 30. The reducing (R) protein migrates as 60-66 kDa in SDS-PAGE due to glycosylation.产品背景:Tyrosine-protein kinase transmembrane receptor ROR1 is also known as Neurotrophic tyrosine kinase, receptor-related 1 (NTRKR1), which belongs to the protein kinase superfamily or tyr protein kinase family or ROR subfamily. ROR1 contains 1 FZ (frizzled) domain, 1 Ig-like C2-type (immunoglobulin-like) domain, 1 kringle domain, 1 protein kinase domain. ROR1 is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. ROR1 could interact with casein kinase 1 epsilon (CK1ε) to activate phosphoinositide 3-kinase-mediated AKT phosphorylation and cAMP-response-element-binding protein (CREB), which was associated with enhanced tumor-cell growth.
免责声明
本网页所展示的有关【Mouse ROR1 Protein】的信息/图片/参数等由的会员【
】提供，由【生物实验采购网】会员【
】自行对信息/图片/参数等的真实性、准确性和合法性负责，本平台（本网站）仅提供展示服务，请谨慎交易，因交易而产生的法
律关系及法律纠纷由您自行协商解决，本平台（本网站）对此不承担任何责任。您在本网页可以浏览【Mouse ROR1 Protein】有关的信息/图片/价格等及提供
【Mouse ROR1 Protein】的商家公司简介、联系方式等信息。
在您的合法权益受到侵害时，请您致电，我们将竭诚为您服务，感谢您对【生物实验采购网】的关注与支持！
点击图片查看原图
LI-1500 光照数据采集器
立可读三聚氰胺检测卡
PrimaCell人肾癌组织源细胞试剂盒
Biotinylated Human V
Biotinylated Human F
Biotinylated Human C
Human VAP-B Protein
Biotinylated Human F
Biotinylated Human T
Human EMMPRIN / CD14
CAR-T靶点蛋白荧光标
