分子量:52.6 kDa纯度:>95% as determined by SDS-PAGE.内毒素:Less than 1.0 EU per μg of the Human DNAM-1, Fc Tag by the LAL method.Buffer:50 mM tris, 100 mM glycine, pH7.5生物活性:产品特性:Human DNAM-1, Fc Tag is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 52.6 kDa. The predicted N-terminus is Glu 19. The reducing (R) protein migrates as 80-90 kDa in SDS-PAGE due to glycosylation.产品背景:DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.
SDS-PAGE
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Biotinylated Human F
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Human EMMPRIN / CD14
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