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FOXO1A 斑马鱼抗体

产品价格: ¥2500.00

最小起订量:暂无 可售数量:999盒

发货时限:
暂无
所在地区:
中国上海
有效期至:
长期有效
最后更新:
2021-05-22 01:30:02
浏览次数:
31

产品详情

品牌名称:
HAbio
货号: ET1608-25
抗体名: FOXO1A 抗体
抗体英文名: FOXO1A
应用范围: ICC IHC WB
宿主: 兔单抗
供应商: 恒斐生物
数量: 大量
级别: 科研
目录编号: ET1608-25
抗原来源:
保质期: 12个月
适应物种: 斑马鱼 , Rat , Mouse , Human ,
克隆性:
保存条件: -20
形态: 液体
规格: 100ul
抗体来源 兔单抗 产品类型 一抗
反应种属 斑马鱼 , Rat , Mouse , Human , 产品应用 ICC IHC WB
储藏条件 -20℃ 产品性状 Liquid
分子量 80 kDa 克隆号  
保质期 12个月 产品品牌 华安
细胞定位 Cytoplasm, Nucleus. 阳性对照 80 kDa
抗体类型 重组兔单抗
其他名称  
抗原介绍 FKHR (for forkhead in rhabdomyosarcoma) and FKHRL1 are members of the forkhead family of transcription factors. Transcriptional activation of FKHR proteins is regulated by the serine/threonine kinase Akt1, which phosphorylates FKHRL1 and results in FKHRL1 associating with 14-3-3 proteins and being retained in the cytoplasm. Induction of apoptosis or withdrawal of growth factors stimulates dephosphorylation and nuclear translocation of FKHR proteins, leading to FKHR-induced gene-specific transcriptional activation. FKHR, also designated forkhead box protein O1A (FOXO1), is a ubiquitously expressed protein that shuttles between the cytoplasm and nucleus. Genetic mutations in FKHR genes, including the t(2;13) and t(1;3) translocations, are commonly found in alveolar rhabdomyosarcomas. These translocations result in the fusion of the amino terminus of Pax-3 or Pax-7, including the paired box and homeodomain DNA-binding domains, with the carboxy-terminus of FKHR, which contains a transcriptional activation domain. The Pax-3/FKHR fusion protein appears to function as an oncogenic transcription factor that enhances the activation of normal Pax-3 target genes.
保存缓冲液 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
特殊性  
   
 
应用介绍  
   
 Recommended Dilutions

WB: 1:1,000-1:2,000   ICC: 1:50-1:200    IHC: 1:50-1:200    
             

                 

Fig1: Western blot analysis of FOXO1A on different lysates
using anti-FOXO1A antibody at 1/1,000 dilution.
Positive control:  
Lane 1: Hela             Lane 2: NIH/3T3

          


Fig2: ICC staining FOXO1A in Hela cells (green). The nuclear counter stain is DAPI (blue).
Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

            

Fig3: ICC staining FOXO1A in MCF-7 cells (green). The nuclear counter stain is DAPI (blue).
Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

            

Fig4: ICC staining FOXO1A in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue).
Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

            
Fig5: Immunohistochemical analysis of paraffin-embedded human tonsil
tissue using anti-FOXO1A antibody. Counter stained with hematoxylin.

            

Fig6: Immunohistochemical analysis of paraffin-embedded human breast carcinoma
tissue using anti-FOXO1A antibody. Counter stained with hematoxylin.

            

Fig7: Immunohistochemical analysis of paraffin-embedded mouse brain tissue
using anti-FOXO1A antibody. Counter stained with hematoxylin.

           

Fig8: Immunohistochemical analysis of paraffin-embedded mouse heart tissue
using anti-FOXO1A antibody. Counter stained with hematoxylin.
FOXO1A
报价:2500
 
  •     货           号ET1608-25
        规           格100ul
     
  •     应           用ICC, IHC, WB,
        反应种属斑马鱼, Rat, Mouse, Human,
     
  •     引用文献
        说   明    书下载
     
  •     星级评价暂无评价
 
Myosin Light Chain 2
报价:2500
 
  •     货           号ET1611-13
        规           格100ul
     
  •     应           用IP, IHC, WB,
        反应种属斑马鱼, Rat, Mouse, Human,
     
  •     引用文献
        说   明    书下载
     
  •     星级评价暂无评价
 
BPI
报价:2500
 
  •     货           号ET1611-6
        规           格100ul
     
  •     应           用FC, WB,
        反应种属斑马鱼, Human,
     
  •     引用文献
        说   明    书下载
     
  •     星级评价暂无评价
 
hnRNP C1+C2
报价:2500
 
  •     货           号ET1611-2
        规           格100ul
     
  •     应           用IP, IF, FC, ICC, IHC, WB,
        反应种属斑马鱼, Rat, Mouse, Human,
     
  •     引用文献
        说   明    书下载
     
  •     星级评价暂无评价
 
NSE
报价:2500
 
  •     货           号ET1610-96
        规           格100ul
     
  •     应           用FC, ICC, IHC, WB,
        反应种属斑马鱼, Rat, Mouse, Human,
     
  •     引用文献
        说   明    书下载
     
  •     星级评价暂无评价
 
IRF7
报价:2500
 
  •     货           号ET1610-89
        规           格100ul
     
  •     应           用IP, IF, FC, ICC, IHC, WB,
        反应种属斑马鱼, Rat, Mouse, Human,
     
  •     引用文献
        说   明    书下载
     
  •     星级评价暂无评价
 
Adiponectin receptor protein 1
报价:2500
 
  •     货           号ET1610-86
        规           格100ul
     
  •     应           用IF, FC, ICC, IHC, WB,
        反应种属斑马鱼, Rat, Mouse, Human,
     
  •     引用文献
        说   明    书下载
     
  •     星级评价暂无评价
 
Ferritin
报价:2500
 
  •     货           号ET1610-78
        规           格100ul
     
  •     应           用IF, ICC, WB,
        反应种属斑马鱼, Rat, Mouse, Human,
     
  •     引用文献
        说   明    书下载
     
  •     星级评价暂无评价
 
S100 beta
报价:2500
 
  •     货           号ET1610-3
        规           格100ul
     
  •     应           用IP, ICC, IHC, WB,
        反应种属斑马鱼, Rat, Mouse, 羊, Human,
     
  •     引用文献
        说   明    书下载
     
  •     星级评价暂无评价
 
Lactate Dehydrogenase
报价:2500
 
  •     货           号ET1608-57
        规           格100ul
     
  •     应           用IP, IF, FC, ICC, IHC, WB,
        反应种属斑马鱼, Rat, Mouse, Human,
     
  •     引用文献
        说   明    书下载
温馨提示:不可用于临床治疗。

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